Advances in the knowledge of parasite resistance of ruminant hosts and parasites

Doenças causadas por parasitas internos e externos estão entre os desafios mais importantes em relação à produção animal. O uso indiscriminado de tratamento antiparasitário pode provocar forte seleção para resistência, bem como gerar resíduos de drogas nos produtos de origem animal e no ambiente.

Este cenário justificou o desenvolvimento da ESPCA - Advances in the knowledge of parasite resistance of ruminant hosts and parasites, 2011, organizada pela Embrapa Pecuária Sudeste sob a coordenação da Pesquisadora Luciana Correia de Almeida Regitano.

A ESCPA reuniu os maiores especialistas em três linhas temáticas: estratégias para utilização da resistência genética do hospedeiro; imunização do hospedeiro; estratégias para detectar e evitar o desenvolvimento de resistência pelos parasitas.

PAÍSES REPRESENTADOS POR ESTUDANTES:
Foram selecionados 42 participantes entre estudantes e profissionais, sendo 24 estrangeiros e 18 brasileiros para apoio financeiro. Os estrangeiros representavam países como Alemanha, Argentina, Bélgica, Benim, Índia, Irã, Irlanda, Nova Zelândia, Paquistão, Peru e Quênia.

PAÍSES REPRESENTADOS POR PALESTRANTES: Brasil, Estados Unidos, Austrália, Alemanha, Reino Unido e Bélgica

  • Intituição

    Empresa Brasileira de Pesquisa Agropecuária (Embrapa)

  • Área de conhecimento

    Medicina Veterinária

  • Pesquisador Responsável

    Luciana Correia de Almeida Regitano

  • Nº do Processo FAPESP

    2010/51534-7

  • Período

    26/09/2011 a 07/10/2011

  • Inscrições

    Encerradas

  • Site

    http://www.cppse.embrapa.br/parasites

  • Cidade

    São Carlos

  • Palavras-chave

    Resistência, Bovino, Ovino, Controle parasitário, Helminto, Ectoparasita

  • Programa Ocultar

    WEEK 1: September 26th to 30th, 2011

    09/26/2011 (Monday)

    08:00-08:30am         Welcome Section - Organizing Committee                  

    08:30-09:30am         FAPESP: Purposes and programs - FAPESP            

    09:30-10:30am         Opening lecture:

    State-of-art of parasite resistance of ruminant hosts - Marcelo Beltrão Molento - Universidade Federal do Paraná, Curitiba, PR, Brazil                      

    10:30-11:00am         Coffee break                       

    11:00-12:30pm         Technical visit to Embrapa Pecuária Sudeste             

    12:30-02:30pm         Lunch interval              

    Theme 1 - Genomics of host resistance to parasites                                                          

    02:30-04:00pm         Genetics of resistance to nematodes in ruminants - Stephen Bishop - Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Scotland, UK                      

    04:00-04:30pm         Coffee break                       

    04:30-06:00pm         Interaction nutrition and immune response - Aurea Canavessi - Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo, Piracicaba, SP, Brazil  
     

    09/27/2011 (Tuesday)

    08:00-08:30am         Research lines and main results obtained at Embrapa Pecuária Sudeste, São Carlos, SP - Luciana Correia de Almeida Regitano - Embrapa Pecuária Sudeste, São Carlos, SP, Brazil

    08:30-10:00am         Gene expression profiling as a tool for understanding host response to ticks - Emily Piper - School of Veterinary Science, The University of Queensland, Australia                       

    10:00-10:30am         Coffee break                       

    10:30-12:00pm         Statistical tools to uncover genetic architecture of tick resistance using high-density oligonucleotide gene expression microarrays - Fernando Flores Cardoso - Embrapa Pecuária Sul, Bagé, RS, Brazil                     

    12:00-02:00pm         Lunch interval                    

    02:00-03:30pm         Genomic selection, perspectives for improving host resistance to parasites - Marcos Vinicius Gualberto Barbosa da Silva - Embrapa Gado de Leite, Juiz de Fora, MG, Brazil            

    03:30-04:00pm         Coffee break                       

    04:00-05:00pm         Theme 1 - Seminar presentation            

    05:00-06:00pm         Theme 1 - Plenary discussion    
     

    09/28/2011 (Wednesday) 

    Theme 2 - Future perspectives of techniques for target validation, vaccine and drug development, and reversal of parasite resistance in endoparasites                                                          

    08:00-09:30am         Immunity against helminths - Alessandro Francisco Talamini do Amarante - Instituto de Biociências, Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil                      

    09:30-09:50am         Presentation of post-graduation programs at Instituto de Biociências de Botucatu, Universidade Estadual Paulista, Botucatu, SP - Alessandro Francisco Talamini do Amarante

    09:50-10:20am         Coffee break                       

    10:20-11:50am         Vaccine development for helminths - Peter Geldhof - Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

    11:50-01:30pm         Lunch interval                    

    01:30-03:00pm         Target identification and validation: challenges of developing antiparasitic drugs – Cristopher Scott Knauer - Veterinary Medicine Research and Development, Pfizer Animal Health, Kalamazoo, USA.                      

    03:00-03:30pm         Coffee break                       

    03:30-05:00pm         Anthelmintic resistance and development of new drugs - Georg von Samson-Himmelstjerna - Institute for Parasitology and Tropical Veterinary Medicine, Freie Universität, Berlin, Germany

    05:00-06:00pm         Poster presentation - Section 1 (Themes 1 and 4)    
     

    09/29/2011 (Thursday)

    08:00-09:30am        RNAi application in parasites - Collette Britton - Division of Veterinary Infection and Immunity, University of Glasgow Veterinary School, Glasgow, Scotland, UK                 

    09:30-10:00am         Coffee break                       

    10:00-11:30am         Reversal of parasite resistance - Marcelo Beltrão Molento - Universidade Federal do Paraná, Curitiba, PR, Brazil              

    11:30-01:30pm         Lunch interval                    

    01:30-02:30pm         Theme 2 - Seminar presentation            

    02:30-03:30pm         Theme 2 - Plenary discussion                

    03:30-04:00pm         Coffee break                       

    04:00-06:00pm         Technical visit to Universidade Federal de São Carlos and Presentation of post-graduation programs at Universidade Federal de São Carlos, São Carlos, SP – Reinaldo Otávio Alvarenga Alves de Brito   
     

    09/30/2011 (Friday)

    08:00-12:00pm         Practical classes (students splited into 4 teams)

    Theme 1 - Gene expression in real time PCR and microarray data analysis (team 1)

    Theme 2 - Reversal of resistance simulation in field (team 2)

    Theme 3 - Egg hatch test and larval development test (team 3)

    Theme 4 - PCR protocols for resistance detection to pyrethroids in the horn fly and ticks (team 4)                               

    02:00-06:00pm         Practical classes

    Theme 1 - team 2

    Theme 2 - team 1

    Theme 3 - team 4

    Theme 4 - team 3   

     

    WEEK 2: October 03rd to 7th, 2011

    10/03/2011 (Monday) 

    Theme 3 - In vitro methods for the diagnostic of anthelmintic resistance and for screening of new bioactive substances          

    08:00-09:30am         Data generated between laboratories looking for evaluation of susceptible and resistant nematodes in cattle - Georg von Samson-Himmelstjerna - Institute for Parasitology and Tropical Veterinary Medicine Free University, Berlin, Germany

    09:30-10:00am         Coffee break                                              

    10:00-11:30pm         Standardization, evaluation and field use of in vitro tests to detect anthelmintic resistance in sheep - Mike Taylor - Veterinary Consultant, Wildlife and emerging Disease Programme Food and Environment Research Agency (FERA), York,UK                      

    11:30-01:30pm         Lunch interval                                            

    01:30-03:00pm         Current challenges and advancements in the use of in vitro tests in the gastrointestinal nematodes in Brazil - Ana Carolina de Souza Chagas - Embrapa Pecuária Sudeste, São Carlos, SP, Brazil

    03:00-04:30pm         A novel approach for combining the use of in vitro and in vivo data to measure and detect emerging moxidectin resistance in gastrointestinal nematodes of goats - Ray M. Kaplan - Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, USA                                             

    04:30-05:00pm         Coffee break                                              

    05:00-06:00pm         Poster presentation – Section 2 (Themes 2 and 3)      
                                                           

    10/04/2011 (Tuesday)

    08:00-09:30am         In vitro methods for screening of plant bioactives for nematode control - Luciana Morita Katiki - Instituto de Zootecnia, Nova Odessa, SP, Brazil                                        

    09:30-10:00am         Coffee break                                              

    10:00-11:00am         Theme 3 - Seminar presentation                                   

    11:00-12:00pm         Theme 3 - Plenary discussion                                        

    12:00-02:00pm         Lunch interval                                            

    02:00-06:00pm         Technical visit to Escola Superior de Agricultura Luiz de Queiroz, USP and Presentation of post-graduation programs at Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo, Piracicaba, SP - Luiz Lehmann Coutinho                     

    10/05/2011 (Wednesday)

    08:00-12:00pm         Practical classes

    Theme 1 - team 3

    Theme 2 - team 4

    Theme 3 - team 1

    Theme 4 - team 2     

    02:00-06:00pm         Practical classes

    Theme 1 - team 4

    Theme 2 - team 3

    Theme 3 - team 2

    Theme 4 - team 1    
     

    10/06/2011 (Thursday) 

    Theme 4 - New perspectives in the control of ruminant ectoparasites                                                          

    08:00-09:30am         Strategies for developing vaccines against cattle ectoparasites: the Rhipicephalus microplus model - Isabel Kinney Ferreira de Miranda Santos - Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

    09:30-10:00am         Presentation of post-graduation programs at Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Jaboticabal, SP - Rosângela Zacarias Machado

    10:00-10:30am         Coffee break           

    10:30-12:00am         Immunopathology of the resistance to ticks - Gervásio Henrique Bechara - Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Jaboticabal, SP, Brazil      

    12:00-02:00pm         Lunch interval        

    02:00-03:30pm         Genetic mutations associated with pesticide resistance in Rhipicephalus microplus and Haematobia irritans - Felix D. Guerrero - Knipling-Bushland USDA, ARS/Livestock Insects Research Laboratory, Kerrville, TX, USA    

    03:30-04:00pm         Coffee break           

    04:00-05:30pm         New resistance management for Haematobia irritans - Lane D. Foil - Louisiana State University, USA      

    05:30-06:00pm         Research lines and main results obtained at Embrapa Pecuária Sudeste, São Carlos, SP - Simone Cristina Méo Niciura - Embrapa Pecuária Sudeste, São Carlos, SP, Brazil
                                                                

    10/07/2011 (Friday)

    08:00-09:30am         Mechanisms of pesticide resistance in insects and ticks - Jeffrey G. Scott - Department of Entomology, Comstock Hall, Cornell University, Ithaca, USA      

    09:30-10:00am         Coffee break           

    10:00-11:00am         Theme 4 - Seminar presentation

    11:00-12:00pm         Theme 4 - Plenary discussion    

    12:00-02:00pm         Lunch interval        

    02:00-03:30pm         Closing Section:

    General discussion and Course evaluation    

    03:30-06:00pm         Social activities